Molecule Information

General Information of the Molecule (ID: Mol02223)

• Name: Long non-protein coding RNA (A_30_P01029806) ,Homo sapiens
• Synonyms: A_30_P01029806
• Molecule Type: LncRNA
• Gene Name: A_30_P01029806

Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens

Type(s) of Resistant Mechanism of This Molecule

  EADR: Epigenetic Alteration of DNA, RNA or Protein

Drug Resistance Data Categorized by Drug

Investigative Drug(s) 1 drug(s) in total

Lipopolysaccharide

Drug Resistance Data Categorized by Their Corresponding Mechanisms

Epigenetic Alteration of DNA, RNA or Protein (EADR)

Disease Class: Acute lung injury [1]

• Resistant Disease: Acute lung injury [ICD-11: NB32.3Z]
• Resistant Drug: Lipopolysaccharide
• Molecule Alteration: Down-regulation; Expression
• Experimental Note: Discovered Using In-vivo Testing Model
• In Vivo Model: ALI mouse model; Mus musculus
• Experiment for Molecule Alteration: Microarray assay
• Experiment for Drug Resistance: CT scan assay
• Mechanism Description: LncRNA A_30_P01029806 and A_30_P01029194, which were down-regulated, were involved in the signaling pathways closely related to ALI.

References

• Ref 1: LncRNA analysis of lung tissues after hUC-MSCs and FTY720 treatment of lipopolysaccharide-induced acute lung injury in mouse modelsInt Immunopharmacol. 2019 Jun;71:68-75. doi: 10.1016/j.intimp.2019.03.017. Epub 2019 Mar 14.