Zalcitabine (ID: DG00888) Resistance Data of HIV

Drug Resistance Data Categorized by Their Corresponding Mechanisms
Aberration of the Drug's Therapeutic Target (ADTT)			Click to Show/Hide
Key Molecule: Gag-Pol polyprotein (POL)				Molecule Info
Resistant Disease	Human immunodeficiency virus infection [ICD-11: 1C62.0]
Molecule Alteration	Alteration Patterns Alteration Types Resistance Mutation Total Point Scores Levels of Drug resistance base on the total point score Ref N.A. Mutation N.A. Resistance [1]
Resistant Drug	Zalcitabine			Drug Info
Experimental Note	Identified from the Human Clinical Data
Mechanism Description	Resistance to zalcitabine usually arises from a series of mutations within the HIV pol gene and develops less frequently than resistance to zidovudine.

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