Molecule Information

General Information of the Molecule (ID: Mol02214)

• Name: Long non-protein coding RNA (MIRT2) ,Homo sapiens
• Synonyms: MIRT2
• Molecule Type: LncRNA
• Gene Name: MIRT2

Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens

Type(s) of Resistant Mechanism of This Molecule

  EADR: Epigenetic Alteration of DNA, RNA or Protein

Drug Resistance Data Categorized by Drug

Investigative Drug(s) 1 drug(s) in total

Picric acid

Drug Resistance Data Categorized by Their Corresponding Mechanisms

Epigenetic Alteration of DNA, RNA or Protein (EADR)

Disease Class: TNF-alpha-triggered inflammation [1]

• Resistant Disease: TNF-alpha-triggered inflammation [ICD-11: 3B81.Z]
• Resistant Drug: Picric acid
• Molecule Alteration: Down-regulation; Interaction
• Experimental Note: Identified from the Human Clinical Data
• Experiment for Molecule Alteration: qRT-PCR; Western bloting analysis; Overexpression assay; Knockdown assay; ELISA assay; Mimic assay
• Mechanism Description: Long non-coding RNA Mirt2 prevents TNF-alpha-triggered inflammation via the repression of microRNA-101.

References

• Ref 1: Long non-coding RNA Mirt2 prevents TNF-Alpha-triggered inflammation via the repression of microRNA-101Int Immunopharmacol. 2019 Nov;76:105878. doi: 10.1016/j.intimp.2019.105878. Epub 2019 Sep 9.