Molecule Information

General Information of the Molecule (ID: Mol02211)

• Name: Long non-protein coding RNA (LNC-CETP-3) ,Homo sapiens
• Synonyms: LNC-CETP-3
• Molecule Type: LncRNA
• Gene Name: LNC-CETP-3

Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens

Type(s) of Resistant Mechanism of This Molecule

  EADR: Epigenetic Alteration of DNA, RNA or Protein

Drug Resistance Data Categorized by Drug

Approved Drug(s) 1 drug(s) in total

Medroxyprogesterone acetate

Drug Resistance Data Categorized by Their Corresponding Mechanisms

Epigenetic Alteration of DNA, RNA or Protein (EADR)

Disease Class: Endometrial adenocarcinoma [1]

• Resistant Disease: Endometrial adenocarcinoma [ICD-11: 2C76.0]
• Resistant Drug: Medroxyprogesterone acetate
• Molecule Alteration: Up-regulation; Expression
• Experimental Note: Revealed Based on the Cell Line Data
• In Vitro Model: Ishikawa cells; Endometrium; Homo sapiens (Human); CVCL_2529
• In Vitro Model: KLE cells; Ovary; Homo sapiens (Human); CVCL_1329
• Experiment for Molecule Alteration: Microarray assay; qRT-PCR
• Mechanism Description: Medroxyprogesterone acetate causes the alterations of endoplasmic reticulum related mRNAs and LncRNAs in endometrial cancer cells.

References

• Ref 1: Medroxyprogesterone acetate causes the alterations of endoplasmic reticulum related mRNAs and lncRNAs in endometrial cancer cellsBMC Med Genomics. 2019 Nov 12;12(1):163. doi: 10.1186/s12920-019-0601-9.