Molecule Information

General Information of the Molecule (ID: Mol02178)

• Name: Sme2 (sme2) ,Schizosaccharomyces pombe
• Synonyms: sme2
• Molecule Type: miscRNA
• Gene Name: sme2
• Gene ID: 5802740

Kingdom: Fungi
Phylum: Ascomycota
Class: Schizosaccharomycetes
Order: Schizosaccharomycetales
Family: Schizosaccharomycetaceae
Genus: Schizosaccharomyces
Species: Schizosaccharomyces pombe

Type(s) of Resistant Mechanism of This Molecule

  EADR: Epigenetic Alteration of DNA, RNA or Protein

Drug Resistance Data Categorized by Drug

Investigative Drug(s) 1 drug(s) in total

Hexane-1,6-diol

Drug Resistance Data Categorized by Their Corresponding Mechanisms

Epigenetic Alteration of DNA, RNA or Protein (EADR)

Disease Class: Fungal infection [1]

• Resistant Disease: Fungal infection [ICD-11: 1F29-1F2F]
• Resistant Drug: Hexane-1,6-diol
• Experimental Note: Identified from the Human Clinical Data
• Experiment for Molecule Alteration: ChIP assay; FISH assay
• Mechanism Description: LncRNA-protein complexes assembled at specific chromosomal loci mediate recognition and subsequent pairing of homologous chromosomes.

References

• Ref 1: Chromosome-associated RNA-protein complexes promote pairing of homologous chromosomes during meiosis in Schizosaccharomyces pombeNat Commun. 2019 Dec 6;10(1):5598. doi: 10.1038/s41467-019-13609-0.