Drug Information
Drug (ID: DG01754) and It's Reported Resistant Information
Name |
Dabrafenib/Trametinib/Vemurafenib
|
||||
---|---|---|---|---|---|
Synonyms |
Dabrafenib/Trametinib/Vemurafenib
Click to Show/Hide
|
||||
Target | . | NOUNIPROTAC | [1] |
Type(s) of Resistant Mechanism of This Drug
UAPP: Unusual Activation of Pro-survival Pathway
Drug Resistance Data Categorized by Their Corresponding Diseases
ICD-02: Benign/in-situ/malignant neoplasm
Gastric cancer [ICD-11: 2B72]
Drug Sensitivity Data Categorized by Their Corresponding Mechanisms | ||||
Unusual Activation of Pro-survival Pathway (UAPP) | ||||
Key Molecule: Serine/threonine-protein kinase B-raf (BRAF) | [1] | |||
Molecule Alteration | Missense mutation | p.V600E (c.1799T>A) |
||
Sensitive Disease | Gastric adenocarcinoma [ICD-11: 2B72.0] | |||
Experimental Note | Identified from the Human Clinical Data |
References
If you find any error in data or bug in web service, please kindly report it to Dr. Sun and Dr. Zhang.