Molecule Information

General Information of the Molecule (ID: Mol02195)
Name
tumor protein p53 pathway corepressor 1 (TP53COR1) ,Homo sapiens
Synonyms
TP53COR1
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Molecule Type
LncRNA
Gene Name
TP53COR1
Gene ID
102800311
HGNC ID
HGNC:43652
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Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Type(s) of Resistant Mechanism of This Molecule
  EADR: Epigenetic Alteration of DNA, RNA or Protein
Drug Resistance Data Categorized by Drug
Approved Drug(s)
1 drug(s) in total
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Chloroquinine phosphate
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Drug Resistance Data Categorized by Their Corresponding Mechanisms
       Epigenetic Alteration of DNA, RNA or Protein (EADR) Click to Show/Hide
Disease Class: Colon cancer [1]
Resistant Disease Colon cancer [ICD-11: 2B90.1]
 Disease Info 
Resistant Drug Chloroquinine phosphate
 Drug Info 
Molecule Alteration Up-regulation
Interaction
Experimental Note Revealed Based on the Cell Line Data
In Vitro Model HT29 Cells Colon Homo sapiens (Human) CVCL_A8EZ
HCT116 cells Colon Homo sapiens (Human) CVCL_0291
Experiment for
Molecule Alteration		 qRT-PCR; Western bloting analysis; Immunoprecipitation; Knockdown assay
Mechanism Description LincRNA-p21 Mediates the Anti-Cancer Effect of Ginkgo Biloba Extract EGb 761 by Stabilizing E-Cadherin Protein in Colon Cancer.
References
Ref 1 lincRNA-p21 Mediates the Anti-Cancer Effect of Ginkgo Biloba Extract EGb 761 by Stabilizing E-Cadherin Protein in Colon CancerMed Sci Monit. 2018 Dec 30;24:9488-9496. doi: 10.12659/MSM.911924.

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