Molecule Information

General Information of the Molecule (ID: Mol02160)

• Name: Matrin 3, pseudogene 2 (Matr3-ps2) ,Mus musculus
• Synonyms: Matr3-ps2
• Molecule Type: LncRNA
• Gene Name: Matr3-ps2
• Gene ID: 17186
• Ensembl ID: ENSMUSG00000089748

Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus

Type(s) of Resistant Mechanism of This Molecule

  EADR: Epigenetic Alteration of DNA, RNA or Protein

Drug Resistance Data Categorized by Drug

Approved Drug(s) 1 drug(s) in total

Insulin recombinant

Drug Resistance Data Categorized by Their Corresponding Mechanisms

Epigenetic Alteration of DNA, RNA or Protein (EADR)

Disease Class: Type 2 diabetes mellitus [1]

• Resistant Disease: Type 2 diabetes mellitus [ICD-11: 5A11.0]
• Resistant Drug: Insulin recombinant
• Molecule Alteration: Up-regulation; Expression
• Experimental Note: Discovered Using In-vivo Testing Model
• In Vitro Model: C2C12 cells; Skeletal muscle; Homo sapiens (Human); CVCL_0188
• In Vivo Model: Male C57BLKS/J db/db mice model; Mus musculus
• Experiment for Molecule Alteration: qRT-PCR
• Mechanism Description: ENSMUST00000160839 was up-regulated in the PA-treated C2C12 myotubes compared with the control cells via qPCR detection.

References

• Ref 1: RNA-sequencing analysis reveals the potential contribution of lncRNAs in palmitic acid-induced insulin resistance of skeletal muscle cellsBiosci Rep. 2020 Jan 31;40(1):BSR20192523. doi: 10.1042/BSR20192523.